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CCT241161

CAT: 0931-T9638-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9638-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1163719-91-2
Target
Raf, Apoptosis, Src
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Apoptosis, MAPK
Purity
>99.99%
Bioactivity
CCT241161 is an orally active pan-RAF inhibitor, with IC50 values of 3, 6, 10, 15, and 30 nM for LCK, CRAF, SRC, V600E-BRAF, and BRAF, respectively. It exhibits significant activity against BRAF and NRAS mutant melanomas and demonstrates anticancer cell proliferative effects [1].
Smiles
N(C(NC1=C(SC)C=C(OC2=C3C(=NC=C2)NC(=O)C=N3)C=C1)=O)C=4N(N=C(C(C)(C)C)C4)C5=CC=CC=C5
Molecular Formula
C28H27N7O3S
Molecular Weight
541.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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