I-BET567

• Target :

  Epigenetic Reader Domain|||Others

• Related Pathways :

  Chromatin/Epigenetic|||Others

• Purity :

  0.998

• Bioactivity :

  I-BET567, a potent pan-BET inhibitor with oral activity, demonstrates pIC50 values of 6.9 and 7.2 for BRD4 BD1 and BD2, respectively. This compound has exhibited efficacy in mouse models of oncology and inflammation [1].

• Smiles :

  C[C@H]1C[C@@H](Nc2ncc(Cl)cn2)c2cc(ccc2N1C(C)=O)C(N)=O

• Molecular Formula :

  C17H18ClN5O2

• Molecular Weight :

  359.81

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1887237-54-8