PF-00835231

• Target:

  SARS-CoV|||HCV Protease|||HIV Protease

• Related Pathways:

  Microbiology/Virology|||Proteases/Proteasome

• Purity:

  0.993

• Bioactivity:

  PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively. PF-00835231 is the active compound of the first anti-3CLpro regimen in clinical trials.

• Smiles:

  COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)CO

• Molecular Formula:

  C24H32N4O6

• Molecular Weight:

  472.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  870153-29-0