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PF-00835231

CAT: 0931-T9458-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9458-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
870153-29-0
Target
SARS-CoV, HCV Protease, HIV Protease
Related Pathways
Microbiology/Virology, Proteases/Proteasome
Purity
0.993
Bioactivity
PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively. PF-00835231 is the active compound of the first anti-3CLpro regimen in clinical trials.
Smiles
COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)CO
Molecular Formula
C24H32N4O6
Molecular Weight
472.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C