MRTX1133

• Target :

  Ras|||Kras

• Related Pathways :

  MAPK|||GPCR/G Protein

• Purity :

  0.996

• Bioactivity :

  MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors.

• Smiles :

  Oc1cc(-c2ncc3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c2F)N2C[C@@H]3CC[C@H](C2)N3)c2c(C#C)c(F)ccc2c1

• Molecular Formula :

  C33H31F3N6O2

• Molecular Weight :

  600.63

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2621928-55-8