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Tolebrutinib

CAT: 0931-T9125-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T9125-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1971920-73-6
Target
BTK
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.992
Bioactivity
Tolebrutinib (PRN2246) is a potent, selective, orally active and brain-penetrant Bruton tyrosine kinase (BTK) inhibitor (IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively) . It exhibits efficacy in central nervous system immunity. Tolebrutinib can be used for the research of multiple sclerosis (MS) .
Smiles
Nc1nccc2n([C@@H]3CCCN(C3)C(=O)C=C)c(=O)n(-c3ccc(Oc4ccccc4)cc3)c12
Molecular Formula
C26H25N5O3
Molecular Weight
455.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
MBS3613549-01Tolebrutinib

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