BI-0115

• Target :

  Lipoxygenase

• Related Pathways :

  Metabolism

• Purity :

  0.9969

• Bioactivity :

  BI-0115 is a selective small molecule inhibitor of LOX-1 that blocks cellular uptake of oxLDL. It binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain. The structure of LOX-1 bound to BI-0115 shows that inter-ligand interactions at the receptor interfaces are key to the formation of the receptor tetramer thereby blocking oxLDL binding.

• Smiles :

  CCCN1c2cccnc2Nc2cc(Cl)ccc2C1=O

• Molecular Formula :

  C15H14ClN3O

• Molecular Weight :

  287.74

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  4929-23-1