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Tuxobertinib

CAT: 0931-T9072-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T9072-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2414572-47-5
Target
RIP kinase, HER, EGFR, BTK
Related Pathways
NF-κB, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Apoptosis, Angiogenesis
Purity
0.9922
Bioactivity
Tuxobertinib (BDTX-189) is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, with KDs of 0.2, 0.76, 13, and 1.2 nM for EGFR, HER2, BLK, and RIPK2, respectively, and exhibits anticancer activity.
Smiles
Clc1cc(Nc2ncnc3cc(OCCN4CCOCC4)c(NC(=O)C=C)cc23)ccc1OCc1ccccn1
Molecular Formula
C29H29ClN6O4
Molecular Weight
561.03
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19166873-01Tuxobertinib
S9786-01Tuxobertinib (BDTX-189)
A22306-5Tuxobertinib (BDTX-189) 5mg
A22306-10Tuxobertinib (BDTX-189) 10mg
A22306-2Tuxobertinib (BDTX-189) 2mg
A22306-200Tuxobertinib (BDTX-189) 200mg
A22306-100Tuxobertinib (BDTX-189) 100mg
A22306-25Tuxobertinib (BDTX-189) 25mg
A22306-50Tuxobertinib (BDTX-189) 50mg
A22306-10mM-DTuxobertinib (BDTX-189) 10mM * 1mL in DMSO

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