PD-089828

• Target:

  FGFR|||EGFR|||PDGFR|||Src

• Related Pathways:

  Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling

• Purity:

  0.9739

• Bioactivity:

  PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFR?, and EGFR (IC50s = 0.15, 1.76, and 5.47 ?M, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 = 0.18 ?M)

• Smiles:

  CC(C)(C)NC(=O)Nc1nc2nc(N)ncc2cc1-c1c(Cl)cccc1Cl

• Molecular Formula:

  C18H18Cl2N6O

• Molecular Weight:

  405.28

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  179343-17-0