GSK046

CAT: 0931-T8932-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T8932-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2474876-09-8
Target
Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Purity
0.9997
Bioactivity
GSK046 (iBET-BD2) is a potent, selective, and orally active BD2 bromodomain inhibitor of the BET proteins, with IC50 values of 264 nM [BRD2 BD2], 98 nM [BRD3 BD2], 49 nM [BRD4 BD2], and 214 nM [BRDT BD2], respectively. It exhibits immunomodulatory activity.
Smiles
C[C@H](Oc1cc(cc(F)c1NC(C)=O)C(=O)N[C@H]1CC[C@H](O)CC1)c1ccccc1
Molecular Formula
C23H27FN2O4
Molecular Weight
414.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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