PRX-07034 hydrochloride

CAT: 0931-T8720-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T8720-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

903580-39-2

Target

5-HT Receptor

Related Pathways

Neuroscience, GPCR/G Protein

Purity

0.9917

Bioactivity

PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and potently decreases food intake and body weight in rodents. PRX-07034 hydrochloride is both a potent (Ki = 4-8 nM) and highly selective 5-HT (6) receptor antagonist (≥100-fold selectivity for the 5-HT (6) receptor compared to 68 other GPCRs, ion channels, and transporters, except D (3) (Ki = 71 nM) and 5-HT (1B) (Ki = 260 nM) receptors.

Smiles

Cl.COc1cc(Cl)cc(C(C)Nc2cc(ccc2S(C)(=O)=O)N2CCNCC2)c1OC

Molecular Formula

C21H29Cl2N3O4S

Molecular Weight

490.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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