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Zingerone

CAT: 0804-HY-14621-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14621-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic and anti-tumor[3] properties[1]. Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways[2]. Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells[3].
CAS Number
122-48-5
Product Name Alternative
Vanillylacetone; Gingerone
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
NF-κB
Type
Natural Products
Related Pathways
NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Zingerone.html
Concentration
10mM
Purity
99.79
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=C(O)C=CC(CCC(C)=O)=C1
Molecular Formula
C11H14O3
Molecular Weight
194.23
Precautions
H315, H319, H335
References & Citations
[1]Ahmad B, et al. A Review on Pharmacological Properties of Zingerone (4- (4-Hydroxy-3-methoxyphenyl) -2-butanone) . ScientificWorldJournal. 2015;2015:816364.|[2]Ahmad B, et al. Zingerone (4- (4-hydroxy-3-methylphenyl) butan-2-one) protects against alloxan-induced diabetes via alleviation of oxidative stress and inflammation: Probable role of NF-kB activation. Saudi Pharm J. 2018 Dec;26 (8) :1137-1145.|[3]Choi JS, et al. Zingerone Suppresses Tumor Development through Decreasing Cyclin D1 Expression and Inducing Mitotic Arrest. Int J Mol Sci. 2018 Sep 19;19 (9) .
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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