GW6471

CAT: 0931-T8486-02Size: 5 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T8486-02Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

880635-03-0

Target

PPAR

Related Pathways

DNA Damage/DNA Repair, Metabolism

Purity

0.9988

Bioactivity

GW6471 is an antagonist of PPARα with IC50 of 0.24 μ M. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.

Smiles

CCC(=O)NC[C@H](Cc1ccc(OCCc2nc(oc2C)-c2ccccc2)cc1)N\C(C)=C/C(=O)c1ccc(cc1)C(F)(F)F

Molecular Formula

C35H36F3N3O4

Molecular Weight

619.67

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

GW6471

a PPARalpha antagonist; structure in first source

CAS Number	880635-03-0
PubChem CID	446738
IUPAC Name	N-[(2S)-3-[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-[[(Z)-4-oxo-4-[4-(trifluoromethyl)phenyl]but-2-en-2-yl]amino]propyl]propanamide
Molecular Formula	C35H36F3N3O4
Molecular Weight	619.7
XLogP	7.9
Topological Polar Surface Area	93.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	14
Heavy Atom Count	45
Formal Charge	0
Complexity	954

SMILES

CCC(=O)NC[C@H](CC1=CC=C(C=C1)OCCC2=C(OC(=N2)C3=CC=CC=C3)C)N/C(=C\C(=O)C4=CC=C(C=C4)C(F)(F)F)/C

InChI

InChI=1S/C35H36F3N3O4/c1-4-33(43)39-22-29(40-23(2)20-32(42)26-12-14-28(15-13-26)35(36,37)38)21-25-10-16-30(17-11-25)44-19-18-31-24(3)45-34(41-31)27-8-6-5-7-9-27/h5-17,20,29,40H,4,18-19,21-22H2,1-3H3,(H,39,43)/b23-20-/t29-/m0/s1

InChIKey

TYEFSRMOUXWTDN-DYQICHDWSA-N

Chemical Structure

2D Structure

CAS: 880635-03-0

CID: 446738

Formula: C35H36F3N3O4

MW: 619.7

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	619.7
XLogP3	7.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	14
Exact Mass	619.26579112
Monoisotopic Mass	619.26579112
Topological Polar Surface Area	93.5 Å²
Heavy Atom Count	45
Formal Charge	0
Complexity	954
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
sc-300779	GW6471
A12413-10	GW6471 10mg
A12413-100	GW6471 100mg
A12413-25	GW6471 25mg
A12413-5	GW6471 5mg

GW6471

Chemical Information

Alternative Products

Popular Products