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SYN1143

CAT: 0931-T8409-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T8409-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
913376-84-8
Target
C-Met/HGFR
Related Pathways
Tyrosine Kinase/Adaptors
Purity
0.9969
Bioactivity
SYN1143 (AMG-1) is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively.
Smiles
COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(CC(C)(C)O)n(-c5ccccc5)c4=O)cc3F)ccnc2c1
Molecular Formula
C31H29FN4O5
Molecular Weight
556.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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