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J14

CAT: 0931-T8320-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T8320-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1043854-13-2
Target
ROS, Reactive Oxygen Species
Related Pathways
NF-κB, Metabolism, Immunology/Inflammation
Purity
0.9951
Bioactivity
J-14 is an inhibitor of reversible sulfiredoxin (IC50 : 8.1 μM) . J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death
Smiles
OC(=O)c1ccc(CSc2nc(cc(n2)-c2ccccc2)N2CCN(CC2)c2ccccc2Cl)cc1
Molecular Formula
C28H25ClN4O2S
Molecular Weight
517.04
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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