Epiberberine chloride

• Target:

  Cholinesterase (ChE) |||Reactive Oxygen Species|||Beta-Secretase|||Antioxidant|||AChR|||BACE|||ROS

• Related Pathways:

  Neuroscience|||Metabolism|||Oxidation-Reduction|||Immunology/Inflammation|||NF-?B

• Purity:

  0.9989

• Bioactivity:

  Epiberberine chloride, a natural pro-berberine from Coptis chinensis Franch. is an AChE, BChE, and BACE1 inhibitor with IC50 values of 1.07, 6.03, and 8.55 ?M, respectively.Epiberberine chloride has antioxidant effects and inhibits the effects of Ca9-22 and Fa2R. Epiberberine chloride has antioxidant effects, inhibits the motility of Ca9-22 and FaDu cell lines, and can be used to study hyperlipidemia, Alzheimer's disease and diabetes.

• Smiles:

  [Cl-].COc1cc2CC[n+]3cc4c5OCOc5ccc4cc3-c2cc1OC

• Molecular Formula:

  C20H18ClNO4

• Molecular Weight:

  371.81

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  889665-86-5