3-Methyl-L-histidine

CAT: 0931-T8274-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0931-T8274-01Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

368-16-1

Target

Endogenous Metabolite

Related Pathways

Metabolism

Purity

0.999

Bioactivity

3-Methylhistidine belongs to the class of organic compounds known as histidine and derivatives. Histidine and derivatives are compounds containing cysteine or a derivative thereof resulting from reaction of cysteine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. It is also a biomarker for the consumption of soy products. 3-Methylhistidine is a very strong basic compound (based on its pKa) . 3-Methylhistidine exists in all eukaryotes, ranging from yeast to humans. In humans, 3-methylhistidine is involved in methylhistidine metabolism. 3-Methylhistidine, with regard to humans, has been found to be associated with several diseases such as diabetes mellitus type 2, eosinophilic esophagitis, and kidney disease; 3-methylhistidine has also been linked to the inborn metabolic disorder propionic acidemia. The measurement of 3-methylhistidine provides an index of the rate of muscle protein breakdown. 3-Methylhistidine is a product of peptide bond synthesis and methylation of actin and myosin. 3-Methylhistidine is a biomarker for meat consumption, especially chicken.Structure

Smiles

Cn1cncc1C[C@H](N)C(O)=O

Molecular Formula

C7H11N3O2

Molecular Weight

169.18

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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3-Methyl-L-histidine

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