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Deserpidine

CAT: 0931-T8270-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T8270-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
131-01-1
Target
RAAS, Angiotensin-converting Enzyme (ACE)
Related Pathways
Endocrinology/Hormones, Metabolism
Purity
0.9859
Bioactivity
Deserpidine (Harmonyl) is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure and for the relief of psychotic behavior.Deserpidine's mechanism of action is through inhibition of the ATP/Mg2+ pump responsible for the sequestering of neurotransmitters into storage vesicles located in the presynaptic neuron. Deserpidine is a competitive angiotensin converting enzyme (ACE) inhibitor. Deserpidine also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex.
Smiles
C(OC)(=O)[C@H]1[C@]2(C[C@@]3(C4=C(C=5C(N4)=CC=CC5)CCN3C[C@]2(C[C@@H](OC(=O)C6=CC(OC)=C(OC)C(OC)=C6)[C@@H]1OC)[H])[H])[H]
Molecular Formula
C32H38N2O8
Molecular Weight
578.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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