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Avacopan

CAT: 0931-T8223-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T8223-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1346623-17-3
Target
Complement System
Related Pathways
Immunology/Inflammation
Purity
0.999
Bioactivity
Avacopan (CCX168) is a C5aR antagonist (IC50=0.1 nM) with selective and oral activity. Avacopan blocks the action of C5a and prevents the development of GN induced by anti-myeloperoxidase antibodies in a mouse model of AAV. Avacopan can be used to treat anti-neutrophil cytoplasmic antibody (ANCA) -related vasculitis.
Smiles
C(=O)(N1[C@H]([C@@H](C(NC2=CC(C(F)(F)F)=C(C)C=C2)=O)CCC1)C3=CC=C(NC4CCCC4)C=C3)C5=C(C)C=CC=C5F
Molecular Formula
C33H35F4N3O2
Molecular Weight
581.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BA5880-5.1Avacopan

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