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Selpercatinib

CAT: 0931-T8222-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T8222-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2152628-33-4
Target
C-RET
Related Pathways
Tyrosine Kinase/Adaptors, Apoptosis
Purity
>99.99%
Bioactivity
Selpercatinib (LOXO-292) is a tyrosine kinase inhibitor with antineoplastic properties, displaying IC50 values of 14.0 nM for RET (WT), 24.1 nM for RET (V804M), and 530.7 nM for RET (G810R) .
Smiles
COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1
Molecular Formula
C29H31N7O3
Molecular Weight
525.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C