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SR8278

CAT: 0931-T7837-07Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T7837-07Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1254944-66-5
Target
REV-ERB, Others
Related Pathways
Metabolism, Others
Purity
0.9973
Bioactivity
SR8278 is an REV-ERBα antagonist (EC50 = 0.47 μM), blocking activation of the receptor by the synthetic agonist GSK 4112
Smiles
CCOC(=O)C1Cc2ccccc2CN1C(=O)c1ccc(SC)s1
Molecular Formula
C18H19NO3S2
Molecular Weight
361.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

SR8278

structure in first source

CAS Number1254944-66-5
PubChem CID53393127
IUPAC Nameethyl 2-(5-methylsulfanylthiophene-2-carbonyl)-3,4-dihydro-1H-isoquinoline-3-carboxylate
Molecular FormulaC18H19NO3S2
Molecular Weight361.5
XLogP4.1
Topological Polar Surface Area100
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Heavy Atom Count24
Formal Charge0
Complexity473
SMILES
CCOC(=O)C1CC2=CC=CC=C2CN1C(=O)C3=CC=C(S3)SC
InChI
InChI=1S/C18H19NO3S2/c1-3-22-18(21)14-10-12-6-4-5-7-13(12)11-19(14)17(20)15-8-9-16(23-2)24-15/h4-9,14H,3,10-11H2,1-2H3
InChIKey
UIEBLUZPSFAFOC-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of SR8278
CAS: 1254944-66-5
CID: 53393127
Formula: C18H19NO3S2
MW: 361.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight361.5
XLogP34.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass361.08063582
Monoisotopic Mass361.08063582
Topological Polar Surface Area100 Ų
Heavy Atom Count24
Formal Charge0
Complexity473
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
MBS5758700SR8278
A22100-25SR8278 25mg
A22100-100SR8278 100mg
A22100-50SR8278 50mg
A22100-10SR8278 10mg
A22100-5SR8278 5mg
A22100-1SR8278 1mg
A22100-10mM-DSR8278 10mM * 1mL in DMSO

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