Ramiprilat

CAT: 0931-T7686-02Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T7686-02Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

87269-97-4

Target

Endogenous Metabolite, Drug Metabolite, Angiotensin-converting Enzyme (ACE), RAAS

Related Pathways

Endocrinology/Hormones, Metabolism

Purity

0.9745

Bioactivity

Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.

Smiles

C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1[C@H]2CCC[C@H]2C[C@H]1C(O)=O

Molecular Formula

C21H28N2O5

Molecular Weight

388.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Ramiprilat

Ramiprilat is a dipeptide that is the active metabolite of ramipril. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, a drug metabolite, a matrix metalloproteinase inhibitor, a cardioprotective agent and a bradykinin receptor B2 agonist. It is a dicarboxylic acid, an azabicycloalkane, a cyclopentapyrrole and a dipeptide. It is a conjugate acid of a ramiprilat(1-).

CAS Number	87269-97-4
PubChem CID	5464096
IUPAC Name	(2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid
Molecular Formula	C21H28N2O5
Molecular Weight	388.5
XLogP	0.7
Topological Polar Surface Area	107
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	8
Heavy Atom Count	28
Formal Charge	0
Complexity	589

SMILES

C[C@@H](C(=O)N1[C@H]2CCC[C@H]2C[C@H]1C(=O)O)N[C@@H](CCC3=CC=CC=C3)C(=O)O

InChI

InChI=1S/C21H28N2O5/c1-13(22-16(20(25)26)11-10-14-6-3-2-4-7-14)19(24)23-17-9-5-8-15(17)12-18(23)21(27)28/h2-4,6-7,13,15-18,22H,5,8-12H2,1H3,(H,25,26)(H,27,28)/t13-,15-,16-,17-,18-/m0/s1

InChIKey

KEDYTOTWMPBSLG-HILJTLORSA-N

Chemical Structure

2D Structure

CAS: 87269-97-4

CID: 5464096

Formula: C21H28N2O5

MW: 388.5

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	388.5
XLogP3	0.7
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	8
Exact Mass	388.19982200
Monoisotopic Mass	388.19982200
Topological Polar Surface Area	107 Å²
Heavy Atom Count	28
Formal Charge	0
Complexity	589
Isotope Atom Count	0
Defined Atom Stereocenter Count	5
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
T1645-01	Ramipril
T84983-01	Ramipril Diketopiperazine Acid

Alternative Products

Catalog	Name
C3492-5	Ramiprilat
HY-A0115R-01	Ramiprilat (Standard)
sc-219946	Ramiprilat-d5
288853-01	Ramiprilat diketopiperazine
MBS6028466-01	Ramiprilat-d3

Ramiprilat

Chemical Information

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