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Talarozole

CAT: 0931-T7370-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T7370-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
201410-53-9
Target
Retinoid Receptor, Autophagy, Cytochromes P450
Related Pathways
Metabolism, Autophagy
Purity
0.98
Bioactivity
Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA) that inhibits CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively, for treating acne, psoriasis, and other keratinization disorders.
Smiles
CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1
Molecular Formula
C21H23N5S
Molecular Weight
377.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C