PLX5622

CAT: 0931-MF-0094988-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0094988-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1303420-67-8
Target
CSF-1R|||c-Fms
Related Pathways
Tyrosine Kinase/Adaptors
Purity
0.9992
Bioactivity
PLX5622 is an orally active small-molecule CSF1R inhibitor that selectively depletes microglia in the brains of mice and rats. It is commonly used to establish models related to microglia-associated neuroinflammation, neurodegenerative diseases (such as Alzheimer's disease and Parkinson's disease), brain injury, and neuroimmune regulation.
Smiles
COc1ncc(F)cc1CNc1ccc(Cc2c[nH]c3ncc(C)cc23)c(F)n1
Molecular Formula
C21H19F2N5O
Molecular Weight
395.41
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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