Pitavastatin

• Target:

  Autophagy|||Mitophagy|||HMG-CoA Reductase|||Apoptosis

• Related Pathways:

  Autophagy|||Apoptosis|||Metabolism

• Purity:

  0.9717

• Bioactivity:

  Pitavastatin (NK-104) is a potent inhibitor of hydroxymethylglutaryl-CoA (HMG-CoA) reductase, effectively inhibiting cholesterol synthesis from acetic acid in HepG2 cells with an IC50 of 5.8 nM. It also induces hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptors and exhibits therapeutic activities such as anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective, and reno-protective effects.

• Smiles:

  C(=C/[C@H](C[C@H](CC(O)=O)O)O)\C1=C(C2=C(N=C1C3CC3)C=CC=C2)C4=CC=C(F)C=C4

• Molecular Formula:

  C25H24FNO4

• Molecular Weight:

  421.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  147511-69-1