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Angiotensin II human

CAT: 0931-T7040-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T7040-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
4474-91-3
Target
Apoptosis, RAAS
Related Pathways
Endocrinology/Hormones, Apoptosis
Purity
>99.99%
Bioactivity
Angiotensin II is a major biologically active vasoconstrictor peptide that regulates blood pressure by binding to AT1R and AT2R receptors. It stimulates the sympathetic nervous system, promotes aldosterone synthesis, and enhances renal function. Additionally, it induces vascular smooth muscle cell proliferation and increases collagen synthesis, leading to vascular and myocardial hypertrophy and fibrosis. It also promotes apoptosis and endothelial capillary formation. Angiotensin II is commonly used to induce hypertension and cardiac hypertrophy animal models.
Smiles
CCC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(NC(=O)C(CCCN=C(N)N)NC(=O)C(N)CC(O)=O)C(C)C)C(=O)NC(Cc1cnc[nH]1)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(O)=O
Molecular Formula
C50H71N13O12
Molecular Weight
1046.18
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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