Schisandrol B

CAT: 0931-MF-0018879-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0018879-01Size:5 mg
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CAS Number
58546-54-6
Target
Autophagy|||Reactive Oxygen Species|||Cytochromes P450|||ROS
Related Pathways
Autophagy|||Metabolism|||Immunology/Inflammation|||NF-?B
Purity
0.9995
Bioactivity
1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-?B and MAPKs signaling pathways. 2. Schisandrol B has anti-inflammatory property, potentially result from the inhibition of COX-2, iNOS, IL-6, TNF-? and NO through the down-regulation of RIP2 and NF-?B activation. 3. Schisandrol B induces marked protective effects against hepatic and renal injury induced by CCl (4) exposure through differential regulation of the MAPK signal transduction pathway. 4. Schisandrol B significantly inhibits cell proliferation in a dose-dependent manner, due to cell cycle arrest in the G1 phase with the downregulation of cyclin D1 expression and Retinoblastoma (RB) phosphorylation.
Smiles
COc1cc2CC(C)(O)C(C)Cc3cc4OCOc4c(OC)c3-c2c(OC)c1OC
Molecular Formula
C23H28O7
Molecular Weight
416.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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Alternative Products

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BUP10550-01Schisandrol B
HY-N0692R-01Schisandrol B (Standard)
371946Schisandrol B discontinued

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