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Praeruptorin C

CAT: 0931-T6S1418-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T6S1418-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
72463-77-5
Target
Calcium Channel, Antioxidant
Related Pathways
Membrane transporter/Ion channel, Oxidation-Reduction, Metabolism
Purity
0.9992
Bioactivity
1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors and regulating the Bcl-2 family. 3. Praeruptorin C can reduce vascular hypertrophy in isolated rat hypertrophied smooth muscle cells, and this is associated with improvement of smooth muscle cells [Ca2+]i level, nitric oxide content and cellular signal transdution of protein kinase C and Gi.
Smiles
C\C=C(\C)C(=O)O[C@@H]1[C@H](OC(=O)CC(C)C)c2c(OC1(C)C)ccc1ccc(=O)oc21
Molecular Formula
C24H28O7
Molecular Weight
428.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C