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Ruscogenin

CAT: 0931-T6S1256-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T6S1256-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
472-11-7
Target
NOD-like Receptor (NLR), NF-κB, NOS
Related Pathways
NF-κB, Immunology/Inflammation
Purity
0.9987
Bioactivity
1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV34) injured by tumor necrosis factor-alpha (TNF-alpha) in a concentration-dependent manner. 3. Ruscogenin significantly attenuate LPS-induced acute lung injury via inhibiting expressions of TF and iNOS and NF-kappa B p65 activation.
Smiles
C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC=C5C[C@@H](O)C[C@@H](O)[C@]5(C)[C@H]4CC[C@]23C)O[C@]11CC[C@@H](C)CO1
Molecular Formula
C27H42O4
Molecular Weight
430.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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