PLX7904

CAT: 0931-MF-0019962-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0019962-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1393465-84-3
Target
Raf
Related Pathways
MAPK
Purity
0.9966
Bioactivity
PLX7904 (PB04), also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells.
Smiles
CCN(C)S(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(cc23)-c2cnc(nc2)C2CC2)c1F
Molecular Formula
C24H22F2N6O3S
Molecular Weight
512.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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