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GW786034B

CAT: 0931-T6930-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T6930-01Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
635702-64-6
Target
PDGFR, c-Kit, VEGFR, FGFR, Autophagy, c-Fms
Related Pathways
Autophagy, Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9987
Bioactivity
Pazopanib Hydrochloride (Votrient HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively.
Smiles
Cl.CN(C1=CC2=NN(C)C(C)=C2C=C1)C1=NC(NC2=CC=C(C)C(=C2)S(N)(=O)=O)=NC=C1
Molecular Formula
C21H23N7O2S·HCl
Molecular Weight
473.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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