MCC950 sodium

• Target:

  NOD-like Receptor (NLR) |||NOD

• Related Pathways:

  Immunology/Inflammation|||NF-?B

• Purity:

  0.998

• Bioactivity:

  MCC950 sodium (CP-456773 sodium) is a potent and selective inhibitor of the inflammatory vesicle NLRP3 (IC50=7.5 nM in BMDMs; IC50=8.1 nM in HMDMs) . MCC950 sodium has no effect on other inflammatory vesicles such as AIM2, NLRC4 or NLRP1.

• Smiles:

  [Na+].CC (C) (O) c1coc (c1) S (=O) (=O) [N-]C (=O) Nc1c2CCCc2cc2CCCc12

• Molecular Formula:

  C20H23N2O5S·Na

• Molecular Weight:

  426.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  256373-96-3