MCC950 sodium

• Target :

  NOD-like Receptor (NLR) |||NOD

• Related Pathways :

  Immunology/Inflammation|||NF-?B

• Purity :

  0.998

• Bioactivity :

  MCC950 sodium (CP-456773 sodium) is a potent and selective inhibitor of the inflammatory vesicle NLRP3 (IC50=7.5 nM in BMDMs; IC50=8.1 nM in HMDMs) . MCC950 sodium has no effect on other inflammatory vesicles such as AIM2, NLRC4 or NLRP1.

• Smiles :

  [Na+].CC(C)(O)c1coc(c1)S(=O)(=O)[N-]C(=O)Nc1c2CCCc2cc2CCCc12

• Molecular Formula :

  C20H23N2O5S·Na

• Molecular Weight :

  426.46

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  256373-96-3