A-1155463

• CAS Number :

  1235034-55-5

• Target :

  Bcl-2 Family

• Related Pathways :

  Apoptosis

• Purity :

  0.99

• Bioactivity :

  A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2 and related proteins BCL-W (Ki=19 nM) and MCL-1 (Ki>440 nM) .

• Smiles :

  C(NC1=NC=2C(S1)=CC=CC2)(=O)C3=C4C(CCN(C4)C5=NC(C(O)=O)=C(CCCOC6=C(F)C=C(C#CCN(C)C)C=C6)S5)=CC=C3

• Molecular Formula :

  C35H32FN5O4S2

• Molecular Weight :

  669.79

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C