SPDP

• Target:

  ADC Linker

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Purity:

  >99.99%

• Bioactivity:

  SPDP is a short-chain crosslinker, which is used for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. SPDP could activate equal amounts of anti-CD11c and anti-CTLA-4 Abs (in borate buffered saline; pH 8.5) .

• Smiles:

  O=C (CCSSc1ccccn1) ON1C (=O) CCC1=O

• Molecular Formula:

  C12H12N2O4S2

• Molecular Weight:

  312.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  68181-17-9