WAY-600

• Target :

  Src|||mTOR|||VEGFR|||PI3K

• Related Pathways :

  Angiogenesis|||Tyrosine Kinase/Adaptors|||PI3K/Akt/mTOR signaling

• Purity :

  0.9988

• Bioactivity :

  WAY-600 is a potent, ATP-competitive, and selective inhibitor of mTOR with an IC50 of 9 nM; it blocks mTORC1/P-S6K (T389) and mTORC2/P-AKT (S473) but not P-AKT (T308), and is selective for mTOR over PI3K? (>100-fold) and PI3K? (>500-fold) .

• Smiles :

  C(N1CCC(CC1)n1ncc2c(nc(nc12)-c1ccc2[nH]ccc2c1)N1CCOCC1)c1cccnc1

• Molecular Formula :

  C28H30N8O

• Molecular Weight :

  494.59

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1062159-35-6