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Ro 31-8220 Mesylate

CAT: 0931-T6643-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T6643-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
138489-18-6
Target
PKC, JNK
Related Pathways
Chromatin/Epigenetic, Cytoskeletal Signaling, MAPK
Purity
0.9918
Bioactivity
Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor for PKC-α/βI/βII/γ/ε (IC50: 5/24/14/27/24 nM), and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.
Smiles
CS(O)(=O)=O.Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCSC(N)=N)c3ccccc23)c2ccccc12
Molecular Formula
C25H23N5O2S·CH4O3S
Molecular Weight
553.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C