Mitoxantrone

• Target:

  Apoptosis|||PKC|||Endogenous Metabolite|||Virus Protease|||Topoisomerase

• Related Pathways:

  Cytoskeletal Signaling|||DNA Damage/DNA Repair|||Apoptosis|||Chromatin/Epigenetic|||Metabolism|||Microbiology/Virology

• Purity:

  0.9874

• Bioactivity:

  Mitoxantrone (mitozantrone) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.

• Smiles:

  OCCNCCNc1ccc (NCCNCCO) c2C (=O) c3c (O) ccc (O) c3C (=O) c12

• Molecular Formula:

  C22H28N4O6

• Molecular Weight:

  444.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  65271-80-9