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Mitoxantrone

CAT: 0931-T6588-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T6588-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
65271-80-9
Target
Apoptosis, PKC, Endogenous Metabolite, Virus Protease, Topoisomerase
Related Pathways
Cytoskeletal Signaling, DNA Damage/DNA Repair, Apoptosis, Chromatin/Epigenetic, Metabolism, Microbiology/Virology
Purity
0.9874
Bioactivity
Mitoxantrone (mitozantrone) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.
Smiles
OCCNCCNc1ccc(NCCNCCO)c2C(=O)c3c(O)ccc(O)c3C(=O)c12
Molecular Formula
C22H28N4O6
Molecular Weight
444.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
FD26022-01Mitoxantrone

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