KU-0060648

CAT: 0931-T6557-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T6557-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

881375-00-4

Target

MTOR, DNA-PK, PI3K

Related Pathways

PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair

Purity

0.9921

Bioactivity

KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 values of 8.6 nM, 4 nM, 0.5 nM, and 0.1 nM respectively, and demonstrates less inhibition of PI3Kγ with an IC50 of 0.59 μM.

Smiles

CCN1CCN(CC(=O)Nc2ccc(-c3cccc4c3oc(cc4=O)N3CCOCC3)c3sc4ccccc4c23)CC1

Molecular Formula

C33H34N4O4S

Molecular Weight

582.71

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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A1769-25	KU-0060648
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