KU-0060648

CAT: 0931-T6557-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T6557-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
881375-00-4
Target
MTOR|||DNA-PK|||PI3K
Related Pathways
PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair
Purity
0.9921
Bioactivity
KU-0060648 is a dual inhibitor of DNA-PK and PI3K?, PI3K?, PI3K? with IC50 values of 8.6 nM, 4 nM, 0.5 nM, and 0.1 nM respectively, and demonstrates less inhibition of PI3K? with an IC50 of 0.59 ?M.
Smiles
CCN1CCN(CC(=O)Nc2ccc(-c3cccc4c3oc(cc4=O)N3CCOCC3)c3sc4ccccc4c23)CC1
Molecular Formula
C33H34N4O4S
Molecular Weight
582.71
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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