KU-0060648

• Target:

  MTOR|||DNA-PK|||PI3K

• Related Pathways:

  PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair

• Purity:

  0.9921

• Bioactivity:

  KU-0060648 is a dual inhibitor of DNA-PK and PI3K?, PI3K?, PI3K? with IC50 values of 8.6 nM, 4 nM, 0.5 nM, and 0.1 nM respectively, and demonstrates less inhibition of PI3K? with an IC50 of 0.59 ?M.

• Smiles:

  CCN1CCN(CC(=O)Nc2ccc(-c3cccc4c3oc(cc4=O)N3CCOCC3)c3sc4ccccc4c23)CC1

• Molecular Formula:

  C33H34N4O4S

• Molecular Weight:

  582.71

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  881375-00-4