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Droxinostat

CAT: 0931-T6481-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T6481-01Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
99873-43-5
Target
Apoptosis, HDAC
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic, Apoptosis
Purity
0.9983
Bioactivity
Droxinostat (NS 41080) is a selective HDAC inhibitor, primarily targeting HDACs 6 and 8 with IC50 values of 2.47 μM and 1.46 μM, respectively. It is over 8-fold more selective against HDAC3 and shows no inhibition for HDAC1, 2, 4, 5, 7, 9, and 10.
Smiles
Cc1cc(Cl)ccc1OCCCC(=O)NO
Molecular Formula
C11H14ClNO3
Molecular Weight
243.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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