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QN523

CAT: 0931-T64374-02Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T64374-02Size:1 mL - 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
878581-60-3
Target
Autophagy, Apoptosis
Related Pathways
Autophagy, Apoptosis
Purity
0.9983
Bioactivity
QN523 represents a novel scaffold with drug-like properties, showing potent in vitro cytotoxicity in a panel of 12 cancer cell lines. QN523 shows significant in vivo efficacy in a pancreatic cancer xenograft model. Autophagy is a major mechanism of action.
Smiles
O=C(Nc1cccc2cccnc12)c1cnccn1
Molecular Formula
C14H10N4O
Molecular Weight
250.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

N-(quinolin-8-yl)pyrazine-2-carboxamide
CAS Number878581-60-3
PubChem CID9463163
IUPAC NameN-quinolin-8-ylpyrazine-2-carboxamide
Molecular FormulaC14H10N4O
Molecular Weight250.25
XLogP1.8
Topological Polar Surface Area67.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Heavy Atom Count19
Formal Charge0
Complexity323
SMILES
C1=CC2=C(C(=C1)NC(=O)C3=NC=CN=C3)N=CC=C2
InChI
InChI=1S/C14H10N4O/c19-14(12-9-15-7-8-16-12)18-11-5-1-3-10-4-2-6-17-13(10)11/h1-9H,(H,18,19)
InChIKey
CYTYVKQBOOTXRP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(quinolin-8-yl)pyrazine-2-carboxamide
CAS: 878581-60-3
CID: 9463163
Formula: C14H10N4O
MW: 250.25
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight250.25
XLogP31.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass250.08546096
Monoisotopic Mass250.08546096
Topological Polar Surface Area67.8 Ų
Heavy Atom Count19
Formal Charge0
Complexity323
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA3296-5QN523

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