Butein

• Target :

  EGFR|||Autophagy|||Apoptosis|||PDE

• Related Pathways :

  Apoptosis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Metabolism|||Autophagy|||Angiogenesis

• Purity :

  >99.99%

• Bioactivity :

  Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator. It sensitizes HeLa cells to Cisplatin by targeting FoxO3a via the AKT and ERK/p38 MAPK pathways.

• Smiles :

  Oc1ccc(C(=O)\C=C\c2ccc(O)c(O)c2)c(O)c1

• Molecular Formula :

  C15H12O5

• Molecular Weight :

  272.25

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  487-52-5