Butein

• Target:

  EGFR|||Autophagy|||Apoptosis|||PDE

• Related Pathways:

  Apoptosis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Metabolism|||Autophagy|||Angiogenesis

• Purity:

  >99.99%

• Bioactivity:

  Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator. It sensitizes HeLa cells to Cisplatin by targeting FoxO3a via the AKT and ERK/p38 MAPK pathways.

• Smiles:

  Oc1ccc(C(=O)\C=C\c2ccc(O)c(O)c2)c(O)c1

• Molecular Formula:

  C15H12O5

• Molecular Weight:

  272.25

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  487-52-5