XP-524

CAT: 0931-MF-0137817-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0137817-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2344825-52-9
Target
Others|||Ras|||Epigenetic Reader Domain|||Kras
Related Pathways
Chromatin/Epigenetic|||Others|||MAPK
Bioactivity
XP-524 is a potent inhibitor of BET and EP300. XP-524 has significant tumouricidal effects in vivo, preventing KRAS-induced tumour transformation in vivo and prolonging survival in two aggressive PDAC transgenic mouse models. XP-524 also enhances the expression of its own peptide and recruitment of tumour cells to cytotoxic T lymphocytes. XP-524 has shown potential for research in pancreatic ductal adenocarcinoma (PDAC) .
Smiles
C(C)(N1C=2C(=C(NS(CC)(=O)=O)C=C(C2)C=3C4=C(N(C)C3)C(=O)NC=C4)C=C1)(C5=CC=CC=N5)C6=CC=CC=N6
Molecular Formula
C30H28N6O3S
Molecular Weight
552.65
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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MBS5806567XP-524
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MBS3844155-01BAY-524
HY-157993-01SAG-524
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