XP-524

• Target :

  Others|||Ras|||Epigenetic Reader Domain|||Kras

• Related Pathways :

  Chromatin/Epigenetic|||Others|||MAPK

• Bioactivity :

  XP-524 is a potent inhibitor of BET and EP300. XP-524 has significant tumouricidal effects in vivo, preventing KRAS-induced tumour transformation in vivo and prolonging survival in two aggressive PDAC transgenic mouse models. XP-524 also enhances the expression of its own peptide and recruitment of tumour cells to cytotoxic T lymphocytes. XP-524 has shown potential for research in pancreatic ductal adenocarcinoma (PDAC) .

• Smiles :

  C(C)(N1C=2C(=C(NS(CC)(=O)=O)C=C(C2)C=3C4=C(N(C)C3)C(=O)NC=C4)C=C1)(C5=CC=CC=N5)C6=CC=CC=N6

• Molecular Formula :

  C30H28N6O3S

• Molecular Weight :

  552.65

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2344825-52-9