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Vamotinib

CAT: 0931-T63746-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T63746-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1416241-23-0
Target
Apoptosis, Tyrosine Kinases, Bcr-Abl
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis, Cytoskeletal Signaling
Purity
0.9964
Bioactivity
Vamotinib (PF-114) is an orally active and specific tyrosine kinase inhibitor with antiproliferative and antitumour activity.Vamotinib inhibits the phosphorylation of BCR/ABL and BCR/ABL-T315I, which promotes apoptosis. Vamotinib is used to study drug-resistant Philadelphia chromosome-positive (Ph+) leukaemia and Alzheimer's disease.
Smiles
CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3nnc4ccccn34)cc2C(F)(F)F)CC1
Molecular Formula
C29H27F3N6O
Molecular Weight
532.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19184877-01Vamotinib

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