HR-19011

• Target:

  PERK

• Related Pathways:

  Apoptosis

• Purity:

  0.9989

• Bioactivity:

  HR-19011 (Compound 40) is an inducer of eIF2? phosphorylation that increases expression levels of downstream proteins ATF and CHOP, exhibiting micromolar-level antiproliferative activity against K562 and PBMC cells.

• Smiles:

  N (C1=C (N[C@H]2CC[C@H] (OC3=CC=C (C (F) (F) F) C=C3) CC2) C (=O) C1=O) C4=CC (C (F) (F) F) =CC (C#N) =C4

• Molecular Formula:

  C25H19F6N3O3

• Molecular Weight:

  523.43

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2851820-52-3