ATR-IN-18

CAT: 0931-T63604-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T63604-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2766407-55-8

Target

ATM/ATR, Others

Related Pathways

Others, PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair

Bioactivity

ATR-IN-18 is an orally active ATR kinase inhibitor (IC50: 0.69 nM) . aTR-IN-18 exhibited anti-proliferative effects in LoVo cells (IC50: 37.34 nM) . aTR-IN-18 showed anti-tumor effects.

Smiles

OC(=O)C(F)(F)F.C[C@@H]1COCCN1c1nc2n(ncc2c2N(CCc12)S(C)(=O)=O)-c1cc[nH]n1

Molecular Formula

C19H22F3N7O5S

Molecular Weight

517.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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ATR-IN-18

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