ATR-IN-18

• Target:

  ATM/ATR|||Others

• Related Pathways:

  Others|||PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair

• Bioactivity:

  ATR-IN-18 is an orally active ATR kinase inhibitor (IC50: 0.69 nM) . aTR-IN-18 exhibited anti-proliferative effects in LoVo cells (IC50: 37.34 nM) . aTR-IN-18 showed anti-tumor effects.

• Smiles:

  OC (=O) C (F) (F) F.C[C@@H]1COCCN1c1nc2n (ncc2c2N (CCc12) S (C) (=O) =O) -c1cc[nH]n1

• Molecular Formula:

  C19H22F3N7O5S

• Molecular Weight:

  517.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2766407-55-8