DENV-IN-4

• Target:

  Others|||DNA/RNA Synthesis

• Related Pathways:

  Others|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

• Bioactivity:

  DENV-IN-4 is a potent inhibitor of DENV (DENV EC50=4.79 ?M, Vero CC50>100 ?M, SI>20.9), demonstrating antiviral efficacy through concentration-dependent reduction of DENV2 expression and inhibition of RNA-dependent RNA polymerase (RdRp) activity.

• Smiles:

  N(N1[C@@H](N2[C@](C1=O)(CC=3C2=CC=CC3)[H])C4=CC=C(O[Si](C(C)(C)C)(C)C)C=C4)C5=CC=C(N(=O)=O)C=C5

• Molecular Formula:

  C28H32N4O4Si

• Molecular Weight:

  516.66

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2762302-75-8