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NVP-BHG712

CAT: 0931-T6348-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T6348-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
940310-85-0
Target
Ephrin Receptor, Raf, Src, Bcr-Abl
Related Pathways
Angiogenesis, MAPK, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling
Purity
0.9863
Bioactivity
NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.
Smiles
Cc1ccc(cc1Nc1nc(nc2n(C)ncc12)-c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F
Molecular Formula
C26H20F3N7O
Molecular Weight
503.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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