Products for Research Use Only

AFM-30a hydrochloride

CAT: 0931-T63423-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63423-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, PAD
Related Pathways
Chromatin/Epigenetic, Others
Bioactivity
AFM-30a hydrochloride is a potent and highly selective inhibitor of protein arginine deiminase 2 (PAD2) . AFM-30a hydrochloride binds to PAD2 (EC50: 9.5 μM) and inhibits H3 guanylation (EC50: 0.4 μM) . AFM-30a hydrochloride can be used to study certain cancers and autoimmune diseases such as rheumatoid arthritis (RA), multiple sclerosis, lupus, and ulcerative colitis.
Molecular Formula
C24H28ClFN6O3
Molecular Weight
502.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C