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NAZ2329

CAT: 0931-T63405-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63405-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2809469-05-2
Target
Others, Phosphatase
Related Pathways
Metabolism, Others
Bioactivity
NAZ2329 is the first cell-permeable inhibitor of the R5 subfamily of receptor-type protein tyrosine phosphatases (RPTPs), which is a variant and preferentially inhibits PTPRZ (IC50=7.5 μM for hPTPRZ1) and PTPRG (IC50=4.8 μM for hPTPRG) compared to other PTPs. NAZ2329 inhibited the tumor growth of glioblastoma cells and exhibited stem cell-like properties compared to the whole (D1 + D2) fragment of PTPRZ.
Smiles
S(CC1=C(OCC)C=CC(C(F)(F)F)=C1)C2=C(C(NS(=O)(=O)C3=CC=CC=C3)=O)SC=C2
Molecular Formula
C21H18F3NO4S3
Molecular Weight
501.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BA8084-10NAZ2329

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