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Pevonedistat

CAT: 0931-T6332-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T6332-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
905579-51-3
Target
E1/E2/E3 Enzyme, Apoptosis, NEDD8
Related Pathways
Metabolism, Ubiquitination, Apoptosis
Purity
0.9992
Bioactivity
Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM) with therapeutic potential for myelodysplastic syndromes (MDS) and antitumor activity.
Smiles
NS(=O)(=O)OC[C@@H]1CC(C[C@@H]1O)n1ccc2c(NC3CCc4ccccc34)ncnc12
Molecular Formula
C21H25N5O4S
Molecular Weight
443.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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