Bafetinib

• Target:

  Autophagy|||Apoptosis|||Src|||Bcr-Abl

• Related Pathways:

  Autophagy|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Angiogenesis|||Apoptosis

• Purity:

  0.9968

• Bioactivity:

  Bafetinib (INNO-406) (INNO-406) is an effective and specific dual Bcr-Abl/Lyn inhibitor (IC50: 5.8/19 nM), and no inhibition of the phosphorylation of the T315I mutant and less effective to c-Kit and PDGFR.

• Smiles:

  CN(C)[C@H]1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cncnc3)c2)C1

• Molecular Formula:

  C30H31F3N8O

• Molecular Weight:

  576.62

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  859212-16-1